Blood pressure & heart rhythm
metoprolol
Women can get higher levels in their blood from the same dose, yet fewer than 2% of its studies looked at women's results separately.
- 41.6%
of the people in the studies were women
- 46%
of studies did not allow pregnant women
- 2%
looked at results for women separately
Was someone like me tested?
Choose the group that fits you.
Not one of these studies reported results separately for any of the groups below.
Pregnant women
46% of studies would not let pregnant women join, and we found no study that tested this medicine in pregnancy.
What do we know?
What the FDA drug label says
Studies that followed pregnant women have not linked it to problems for the baby. Uncontrolled high blood pressure in pregnancy is risky in itself.
Good to know
Women tend to reach higher blood levels of metoprolol than men on the same dose, but the dose is the same for everyone.
What women report more
Compared with men taking the same medicine.
- 2.7×Food intolerance
- 2.0×Changes to the front of the eye
- 1.9×Broken bones
- 1.9×Hair, nail and sweat-gland problems
How many times more often women reported each problem than men taking the same medicine, based on reports to the FDA. This is a warning sign, not proof the medicine caused it.
Make it about you
Check it against your medicines
Check metoprolol against the medicines, pregnancy and birth control in your profile.
Join to checkAll the details
Every number behind this page.
Who was in the studies
18,934 people in 58 studies
Race
- White91.5%
- Black / African American7.2%
- Other0.4%
- Asian0.4%
- Hispanic / Latina0.1%
Studies didn't say how many of the women were Black, Asian or another race — only totals for everyone.
- Hispanic or Latina
- 7.2%
- Age 65 or older
- 31.2%
- Studies with men only
- 1
- Studies with women only
- 3
Rules that kept women out
Share of studies with each rule.
- 66%
No heart disease
Women with heart disease, heart rhythm problems or a past heart attack were turned away.
See the exact rule
“Known cardiovascular disease (including history of angina pectoris, heart failure, presence of a cardiac pacemaker, history of myocardial infarction or revascularization procedure, or cerebrovascular disease, including stroke and TIA)” NCT01203852
- 46%
No pregnant women
Women who were pregnant could not join.
See the exact rule
“Pregnancy or lactation” NCT01203852
- 34%
No diabetes
Women with diabetes were turned away.
See the exact rule
“Diabetes mellitus (Type 1 or 2)” NCT01203852
- 24%
No mental health conditions
Women with depression, bipolar disorder or other mental health conditions were turned away.
See the exact rule
“A serious physician-recorded psychiatric morbidity that would interfere with the study” NCT00241904
- 20%
No breastfeeding moms
Women who were breastfeeding could not join.
See the exact rule
“Pregnancy or lactation” NCT01203852
- 20%
Only women past menopause
Women who could still get pregnant were turned away.
See the exact rule
“Must be postmenopausal or taking some form of birth control of surgically sterile” NCT00829296
What nobody checked
Share of studies that recorded each thing.
- 2%Results shown separately for women
- 0%Whether anyone was pregnant
- 0%Whether women were past menopause
- 9%Body weight (BMI)
- 31%Hispanic / Latina or not
- 46%Race
All 59 studies
Study titles and rules are shown in their original English.