Women were less than half of the people tested for almost all of these common medicines.
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NCT01370590

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)

See it on ClinicalTrials.gov ↗

406 people

248 womenmiddle line = equal numbers158 men
Phase
PHASE3
Paid for by
Organon and Co
Finished
2012-04
Health conditions
Hypercholesterolemia
Who could join
Anyone
Ages
18 Years – 79 Years
Average age
Not reported
Age 65+
17%
Weight (BMI)
Not reported
Pregnancy recorded
Not reported
Menopause recorded
Not reported
Results shown by sex
Not split by sex
Race
Not reported

Women left out

  • No pregnant women

    Women who were pregnant could not join.

    “Is pregnant or lactating.”
  • No breastfeeding moms

    Women who were breastfeeding could not join.

    “Is pregnant or lactating.”
  • Had to use birth control

    Women who couldn't or didn't want to use birth control were turned away.

    “Female of reproductive potential agrees to remain abstinent or to use (or have their partner use) 2 acceptable methods of birth control throughout the study.”
  • No kidney or liver problems

    Women with kidney or liver problems were turned away.

    “…pass, or other significant intestinal malabsorption; uncontrolled hypertension; kidney disease; disease known to influence serum lipids or lipoproteins; hematologic, digestive, or central nervous systems disorder; known to be human immunode…”
  • No heart disease

    Women with heart disease, heart rhythm problems or a past heart attack were turned away.

    “Is high risk (according to NCEP ATP III guidelines), including but not limited to one or more of the following: diabetes mellitus (Type I or II), myocardial infarction, coronary artery bypass surgery, angioplasty, stable or unstable angina.”
  • No diabetes

    Women with diabetes were turned away.

    “Is high risk (according to NCEP ATP III guidelines), including but not limited to one or more of the following: diabetes mellitus (Type I or II), myocardial infarction, coronary artery bypass surgery, angioplasty, stable or unstable angina.”
  • No mental health conditions

    Women with depression, bipolar disorder or other mental health conditions were turned away.

    “…for adequately treated basal cell or squamous cell skin cancer or in situ cervical cancer; mental instability; drug/alcohol abuse within the past 5 years, or major psychiatric illness not adequately controlled and stable on pharmacotherapy.”
  • No cancer

    Women with current or past cancer were turned away.

    “…s disorder; known to be human immunodeficiency virus (HIV) positive; history of malignancy ≤5 years prior to the study, except for adequately treated basal cell or squamous cell skin cancer or in situ cervical cancer; mental instability; dr…”

Study titles and rules are shown in their original English.