Women were less than half of the people tested for almost all of these common medicines.
PregnancyCommunity forum

NCT03768427

Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)

See it on ClinicalTrials.gov ↗

454 people

161 womenmiddle line = equal numbers293 men
Phase
PHASE3
Paid for by
Organon and Co
Finished
2021-04-01
Health conditions
Hypercholesterolemia
Who could join
Anyone
Ages
18 Years – 80 Years
Average age
mean 60.9 Years
Age 65+
Not reported
Weight (BMI)
Not reported
Pregnancy recorded
Not reported
Menopause recorded
Not reported
Results shown by sex
Not split by sex
Race
Asian 100% · American Indian / Alaska Native 0% · Native Hawaiian / Pacific Islander 0% · Black / African American 0% · White 0% · More than one race 0% · Not reported 0%

Women left out

  • No pregnant women

    Women who were pregnant could not join.

    “Is a WOCBP who has had a positive urine pregnancy test within 24 hours before the first dose of study intervention. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required.”
  • No women who could get pregnant

    Most women roughly 15–50 years old were turned away.

    “Is a WOCBP who has had a positive urine pregnancy test within 24 hours before the first dose of study intervention. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required.”
  • Had to use birth control

    Women who couldn't or didn't want to use birth control were turned away.

    “If female, is not pregnant or breastfeeding, and is either not a woman of childbearing potential (WOCBP), or is a WOCBP who has used a contraceptive consistent with local regulations.”
  • No hormonal birth control

    Women on the pill, patch, ring, shot, implant or hormonal IUD could not join.

    “Is taking any cyclical hormones (e.g., cyclical oral contraceptives, cyclical hormone replacement), including the combination of ethinyl estradiol and norethisterone, or non-cyclical hormones, including non-cyclical hormone replacement ther…”
  • No hormone therapy

    Women taking menopause hormones or gender-affirming hormones could not join.

    “Is taking any cyclical hormones (e.g., cyclical oral contraceptives, cyclical hormone replacement), including the combination of ethinyl estradiol and norethisterone, or non-cyclical hormones, including non-cyclical hormone replacement ther…”
  • No kidney or liver problems

    Women with kidney or liver problems were turned away.

    “Has active liver disease”
  • No heart disease

    Women with heart disease, heart rhythm problems or a past heart attack were turned away.

    “Has New York Heart Association (NYHA) Class III or IV symptomatic congestive heart failure at Visit 1.”
  • No mental health conditions

    Women with depression, bipolar disorder or other mental health conditions were turned away.

    “Has a history of mental instability, drug/alcohol abuse within the past 5 years, or major psychiatric illness not adequately controlled and stable on pharmacotherapy.”
  • No cancer

    Women with current or past cancer were turned away.

    “Has a history of cancer within the past 5 years from Visit 1 (except for successfully treated dermatological basal cell or squamous cell carcinoma or in situ cervical cancer).”

Study titles and rules are shown in their original English.