High blood pressure
lisinopril
One of the most prescribed blood-pressure pills, and not one study we found looked at women's results separately.
- 42.5%
of the people in the studies were women
- 47%
of studies did not allow pregnant women
- 0%
looked at results for women separately
Was someone like me tested?
Choose the group that fits you.
Not one of these studies reported results separately for any of the groups below.
Pregnant women
47% of studies would not let pregnant women join, and we found no study that tested this medicine in pregnancy.
What do we know?
What the FDA drug label says
Can seriously harm or kill an unborn baby, especially in the 2nd and 3rd trimesters. Stop taking it as soon as you know you are pregnant, and talk to your doctor.
Good to know
A dry, nagging cough is a common side effect and is reported more often by women.
What women report more
Compared with men taking the same medicine.
- 2.9×Changes to the front of the eye
- 2.4×Joint lining and bursa swelling
- 2.1×Ear problems
- 2.0×Broken bones
How many times more often women reported each problem than men taking the same medicine, based on reports to the FDA. This is a warning sign, not proof the medicine caused it.
Make it about you
Check it against your medicines
Check lisinopril against the medicines, pregnancy and birth control in your profile.
Join to checkAll the details
Every number behind this page.
Who was in the studies
18,559 people in 34 studies
Race
- White89.7%
- Black / African American8.8%
- Asian0.7%
- American Indian / Alaska Native0.2%
- More than one race0.2%
Studies didn't say how many of the women were Black, Asian or another race — only totals for everyone.
- Hispanic or Latina
- 9.3%
- Age 65 or older
- 8.1%
- Studies with men only
- 2
- Studies with women only
- 0
Rules that kept women out
Share of studies with each rule.
- 59%
No heart disease
Women with heart disease, heart rhythm problems or a past heart attack were turned away.
See the exact rule
“uncontrollable or symptomatic arrhythmias unstable angina or angina treated with a beta-blocker sick sinus syndrome or second or third degree heart block (unless treated with a permanent, functioning pacemaker) bradycardia (sitting heart ra…” NCT00347360
- 47%
No pregnant women
Women who were pregnant could not join.
See the exact rule
“Females must be post-menopausal, or not pregnant and using an approved contraceptive regimen” NCT01218100
- 38%
No diabetes
Women with diabetes were turned away.
See the exact rule
“Subject has DBP =90 mmHg (or for diabetic subjects, DBP =80 mmHg) on two antihypertensive medications.” NCT00347360
- 27%
Had to use birth control
Women who couldn't or didn't want to use birth control were turned away.
See the exact rule
“Females must be post-menopausal, or not pregnant and using an approved contraceptive regimen” NCT01218100
- 21%
No breastfeeding moms
Women who were breastfeeding could not join.
See the exact rule
“Pregnancy or lactation.” NCT02336607
- 21%
Age limit under 65
Older women were turned away, even though they often take this medicine.
See the exact rule
“Maximum age: 64 Years.” NCT01218100
What nobody checked
Share of studies that recorded each thing.
- 0%Results shown separately for women
- 0%Whether anyone was pregnant
- 0%Whether women were past menopause
- 15%Body weight (BMI)
- 15%Hispanic / Latina or not
- 53%Race
All 34 studies
Study titles and rules are shown in their original English.