Women were less than half of the people tested for almost all of these common medicines.
PregnancyCommunity forum

NCT00425373

Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential Hypertension

See it on ClinicalTrials.gov ↗

1,468 people

405 womenmiddle line = equal numbers1,063 men
Phase
PHASE2, PHASE3
Paid for by
Novartis Pharmaceuticals
Finished
2008-03
Health conditions
Essential Hypertension
Who could join
Anyone
Ages
20 Years – 80 Years
Average age
mean 53.1 years
Age 65+
Not reported
Weight (BMI)
Not reported
Pregnancy recorded
Not reported
Menopause recorded
Not reported
Results shown by sex
Not split by sex
Race
Not reported

Women left out

  • No pregnant women

    Women who were pregnant could not join.

    “Pregnant women, nursing (lactating) mothers, women suspected of being pregnant, or women who wish to be pregnant during the study, women of child-bearing potential.”
  • No breastfeeding moms

    Women who were breastfeeding could not join.

    “Pregnant women, nursing (lactating) mothers, women suspected of being pregnant, or women who wish to be pregnant during the study, women of child-bearing potential.”
  • No women who could get pregnant

    Most women roughly 15–50 years old were turned away.

    “Pregnant women, nursing (lactating) mothers, women suspected of being pregnant, or women who wish to be pregnant during the study, women of child-bearing potential.”
  • No kidney or liver problems

    Women with kidney or liver problems were turned away.

    “Patients with or with a history of any of the following diseases or signs: Cardiac disease, renal disease, cerebrovascular disorder”
  • No heart disease

    Women with heart disease, heart rhythm problems or a past heart attack were turned away.

    “Patients with or with a history of any of the following diseases or signs: Cardiac disease, renal disease, cerebrovascular disorder”
  • No diabetes

    Women with diabetes were turned away.

    “Patients with type I diabetes mellitus on treatment with insulin, or patients with type II diabetes with poor glucose control defined as a glycosylated hemoglobin (HbA1c) \> 8.0% at Visit 1.”
  • No cancer

    Women with current or past cancer were turned away.

    “Patients with a history of malignant hypertension.”

Study titles and rules are shown in their original English.