Women were less than half of the people tested for almost all of these common medicines.
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NCT00546052

A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)

See it on ClinicalTrials.gov ↗

1,714 people

734 womenmiddle line = equal numbers980 men
Phase
PHASE3
Paid for by
Organon and Co
Finished
2008-01-01
Health conditions
Hypertension, Metabolic Disorder
Who could join
Anyone
Ages
18 Years – no maximum
Average age
mean 54.93 Years
Age 65+
19%
Weight (BMI)
mean 33.23 Kg/m2
Pregnancy recorded
Not reported
Menopause recorded
Not reported
Results shown by sex
Not split by sex
Race
White 84.7% · Asian 11.7% · Black / African American 1.9% · Other 1.1% · American Indian / Alaska Native 0.6% · Not reported 0.1%

Women left out

  • No pregnant women

    Women who were pregnant could not join.

    “Pregnant Woman Or A Woman Of Childbearing Potential”
  • No women who could get pregnant

    Most women roughly 15–50 years old were turned away.

    “Pregnant Woman Or A Woman Of Childbearing Potential”
  • Weight limit (BMI)

    Women with a higher (or lower) body weight were turned away.

    “abdominal (central) obesity as defined by the waist circumference in men of \> 102 cm and women of \> 88 cm or a BMI equal or greater than 30 kg/m2”
  • No kidney or liver problems

    Women with kidney or liver problems were turned away.

    “Patient With Confirmed Clinically Significant Renal Or Hepatic Dysfunction And/Or Electrolyte Imbalance On The Basis Of The Case History Or A Recent Laboratory Test (Serum Creatinine \> 130 Mmol/L Or Creatinine Clearance \< 45 Ml/Min, Ast \…”
  • No heart disease

    Women with heart disease, heart rhythm problems or a past heart attack were turned away.

    “Patient With Symptomatic Heart Failure (Classes 3 And 4)”
  • No diabetes

    Women with diabetes were turned away.

    “A Patient With A Diagnosis Of Type II Diabetes Defined As Fasting Blood Glucose Level Equal Or Greater Than 7.0 Mmol/L Or A 2hpg In A 75-G OGTT Equal Or Greater Than 11.1 Mol/L Or Using Any Anti-Hyperglycemic Agents”
  • No cancer

    Women with current or past cancer were turned away.

    “Known Secondary Hypertension Of Any Aetiology (E.G., Uncorrected Renal Artery Stenosis, Malignant Hypertension, Or Hypertensive Encephalopathy)”

Study titles and rules are shown in their original English.