High blood pressure
losartan
About half of people with high blood pressure are women, but they were only 39% of the people in its studies.
- 39.2%
of the people in the studies were women
- 57%
of studies did not allow pregnant women
- 0%
looked at results for women separately
Was someone like me tested?
Choose the group that fits you.
Not one of these studies reported results separately for any of the groups below.
Pregnant women
57% of studies would not let pregnant women join. Only 1 small study (11 women in all) looked at pregnancy or just after birth.
What do we know?
What the FDA drug label says
Can seriously harm or kill an unborn baby, especially in the 2nd and 3rd trimesters. Stop taking it as soon as you know you are pregnant, and talk to your doctor.
Studies focused on this group (1)
- Losartan for Improved Vascular Endothelial Function After Preeclampsia · 11 people · results posted
What women report more
Compared with men taking the same medicine.
- 2.2×Broken bones
- 1.9×Bone and joint injuries
- 1.7×Headaches
- 1.7×Hair, nail and sweat-gland problems
How many times more often women reported each problem than men taking the same medicine, based on reports to the FDA. This is a warning sign, not proof the medicine caused it.
Make it about you
Check it against your medicines
Check losartan against the medicines, pregnancy and birth control in your profile.
Join to checkAll the details
Every number behind this page.
Who was in the studies
19,050 people in 74 studies
Race
- White73.9%
- Black / African American14.4%
- Asian4.8%
- Other2.5%
- Hispanic / Latina1.9%
Studies didn't say how many of the women were Black, Asian or another race — only totals for everyone.
- Hispanic or Latina
- 17.6%
- Age 65 or older
- 31.8%
- Studies with men only
- 2
- Studies with women only
- 1
Rules that kept women out
Share of studies with each rule.
- 57%
No pregnant women
Women who were pregnant could not join.
See the exact rule
“Pregnant Woman Or A Woman Of Childbearing Potential” NCT00546052
- 55%
No heart disease
Women with heart disease, heart rhythm problems or a past heart attack were turned away.
See the exact rule
“Patient With Symptomatic Heart Failure (Classes 3 And 4)” NCT00546052
- 38%
No diabetes
Women with diabetes were turned away.
See the exact rule
“A Patient With A Diagnosis Of Type II Diabetes Defined As Fasting Blood Glucose Level Equal Or Greater Than 7.0 Mmol/L Or A 2hpg In A 75-G OGTT Equal Or Greater Than 11.1 Mol/L Or Using Any Anti-Hyperglycemic Agents” NCT00546052
- 32%
No breastfeeding moms
Women who were breastfeeding could not join.
See the exact rule
“Women of childbearing potential or who are breastfeeding” NCT00882440
- 32%
No cancer
Women with current or past cancer were turned away.
See the exact rule
“Known Secondary Hypertension Of Any Aetiology (E.G., Uncorrected Renal Artery Stenosis, Malignant Hypertension, Or Hypertensive Encephalopathy)” NCT00546052
- 23%
No mental health conditions
Women with depression, bipolar disorder or other mental health conditions were turned away.
See the exact rule
“…/metabolic (with the exception of non-insulin, dependent type 2 diabetes mellitus with HbA1c \< 9.5% at Screening), hematologic/oncologic (including an active malignancy other than basal cell carcinoma), neurologic and psychiatric diseases.” NCT00949884
What nobody checked
Share of studies that recorded each thing.
- 0%Results shown separately for women
- 0%Whether anyone was pregnant
- 0%Whether women were past menopause
- 14%Body weight (BMI)
- 14%Hispanic / Latina or not
- 60%Race
All 74 studies
Study titles and rules are shown in their original English.