Women were less than half of the people tested for almost all of these common medicines.
PregnancyCommunity forum

NCT04518293

Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension

See it on ClinicalTrials.gov ↗

1,385 people

712 womenmiddle line = equal numbers673 men
Phase
PHASE3
Paid for by
George Medicines PTY Limited
Finished
2023-09-01
Health conditions
Hypertension
Who could join
Anyone
Ages
18 Years – no maximum
Average age
mean 59.0 Years
Age 65+
Not reported
Weight (BMI)
mean 28.86 Kg/m^2
Pregnancy recorded
Not reported
Menopause recorded
Not reported
Results shown by sex
Not split by sex
Race
Asian 48.6% · White 45.6% · Black / African American 5.1% · Native Hawaiian / Pacific Islander 0.6% · American Indian / Alaska Native 0.1% · More than one race 0.1% · Not reported 0%

Women left out

  • No pregnant women

    Women who were pregnant could not join.

    “Pregnant or had a positive pregnancy test or unwilling to undertake a pregnancy test during the trial and up to 30 days after the discontinuation of the trial medication or breastfeeding or of childbearing age and not using an acceptable me…”
  • No breastfeeding moms

    Women who were breastfeeding could not join.

    “…he trial and up to 30 days after the discontinuation of the trial medication or breastfeeding or of childbearing age and not using an acceptable method of contraception. Acceptable methods of birth control include hormonal prescription oral…”
  • No hormonal birth control

    Women on the pill, patch, ring, shot, implant or hormonal IUD could not join.

    “…ontraception. Acceptable methods of birth control include hormonal prescription oral contraceptives, contraceptive injections, contraceptive patch, intrauterine device, double-barrier method (e.g. condoms, diaphragm, or cervical cap with sp…”
  • No kidney or liver problems

    Women with kidney or liver problems were turned away.

    “Current/history of end-stage renal disease or anuria or estimated glomerular filtration rate (eGFR) \<60 ml/min/1.73m2.”
  • No heart disease

    Women with heart disease, heart rhythm problems or a past heart attack were turned away.

    “Receiving any BP lowering drugs for indications other than hypertension e.g. heart failure”
  • No diabetes

    Women with diabetes were turned away.

    “Current/history of substantially uncontrolled diabetes (HbA1c \> 11.0%) within last three months.”

Study titles and rules are shown in their original English.